Director Vincenzo Natali is developing a movie based on William Gibson's seminal cyberpunk novel Neuromancer. It's early days for the project, but the director sounds confident that time has caught up with the novel and that it is now possible to write a faithful adaptation.
Meanwhile, Legendary Pictures have picked up the movie rights to the Mass Effect series of computer roleplaying games. BioWare are working on a trilogy of games set in the SF universe (which depicts humanity as the junior member of an alliance of various races facing the threat of the alien Reapers in 2183) and released Mass Effect 2 earlier this year to critical acclaim.
Interesting to see if either of these projects make it to the movie screen in good shape.