From left to right, Olivia Williams, Nick Frost and Ann Skelly.
Laura Donnelly (Outlander) is playing protagonist Amalia True, "the most reckless, impulsive, emotionally damaged hero of her time."
Olivia Williams (Dollhouse) is playing Lavinia Bidlow, a wealther spinster and champion of the Touched. She is the founder of the Orphanage, where Amalia and many of the Touched live.
James Norton (Grantchester) as Hugo Swann, a club owner who collects information and intelligence. He is fascinated by the Touched and may or may not be an ally.
Tom Riley (Da Vinci's Demons) as Augustus Bidlow, Lavinia's younger brother, Hugo's best friend and keen ornithologist. He develops an infatuation with one of the Touched.
Ann Skelly (Little Women) as Penance Adair, Amalia's dearest friend and a fellow member of the Touched. She is a devout Irish Catholic, which guides her moral choices.
Ben Chaplin (Snowden) as Detective Frank Mundi, a police officer with a sense of morality but who is driven to drink by the moral quandaries he finds himself in. He runs afoul of the rich and powerful, who ignore the laws of the land, and becomes aware of the presence of the Touched in London.
Pip Torrens (The Crown) as Lord Massen. A former general in the British Army and now a Peer of the Realm, Massen fears that the Touched are a danger to the Empire.
Zackary Momoh (Seven Seconds) as Dr. Horation Cousens. Another of the Touched and an ally of Amalia. As a doctor with a wife and son, he has a respectable place in society.
Amy Manson (Being Human) as Maladie, another of the Touched but one who has been driven mad by its powers. She now lives underground and has been blamed for a murder spree.
Nick Frost (Into the Badlands, Shaun of the Dead, Hot Fuzz) as Declan Orrun, the Beggar King. Charismatic but brutal, Declan runs most of the crime gangs in the city. He has been both an ally and an enemy of the Touched, as he is happy to back them in return for favours but also doesn't have a problem selling them out to a higher bidder.
Rochelle Neil (Episodes) as Annie Carbey, aka Bonfire, a career criminal and one of the Touched, with the power to manipulate fire. She is a lone operator and not interested in working with others.
Eleanor Tomlinson (Poldark) as Mary Brighton, an aspiring singer.
Denis O'Hare (Big Little Lies) as Dr. Edmund Hague, a gifted American surgeon.
The Nevers started shooting last month in London and should air on HBO in mid-to-late 2020.