The already-announced project is code-named "Polaris," although in reality it's being informally called The Witcher 4. The game picks up after the events of The Witcher 3: Wild Hunt and its expansions; is a large-scale, open-world CRPG; will probably not focus on Geralt as the main character (based on previous statements); will use the Unreal 5 Engine; and is the beginning of a new Witcher trilogy. The game currently has 150 people working on it internally at CDPR.
Obviously as part of that announcement, CDPR have also confirmed that effectively The Witcher 5 and 6 (though they probably won't be called that) are also in the planning. The plan is to release the two sequels at 3-year intervals after the initial release, which will be ambitious.
Alongside that is "Sirius," an "innovative take on The Witcher universe telling an unforgettable story for existing Witcher fans and new audiences." This game is being worked on the Molasses Flood, an American studio based in Boston which CDPR acquired a year ago. The developer is known for their survival and base-building games, The Flame in the Flood and Drake Hollow, suggesting this will not be an RPG but a different genre within the same world.
"Canis Majoris" is the final title and is, intriguingly, "a story-driven, single-player, open-world RPG set within The Witcher universe." It is being worked on by a 3rd-party studio led by ex-Witcher veterans from CDPR.
CDPR - perhaps unwisely given how this turned out last time - have also confirmed they are working on "Orion," a full sequel to Cyberpunk 2077. That makes sense since, despite its rocky launch, the original game has now sold over 20 million copies. Although not confirmed by CDPR, it's likely this game will also move to Unreal Engine 5. It has no title, though fans are inevitably already calling it Cyberpunk 2078.
This is in addition to Cyberpunk 2077: Phantom Liberty, the major story expansion to Cyberpunk 2077 and the current primary focus for the company, with over 350 people involved. This title is set to launch in 2023.
CDPR have also teased "Hadar," a third, new IP project, which is in the very earliest prototyping stage.