There's not much to go on in the image, but it confirms that the story will begin in Vault 33 (as indicated by set images released a few months ago). Vault 33 has not appeared or even been mentioned before in any prior Fallout content, seemingly confirming that this will be a completely new story in the same world, not an adaptation of any of the existing games.
The classic image of the Vault staff watching one of their number leave the Vault on some mission or quest into the Wasteland will be very familiar, as it's effectively how both the original Fallout and Fallout 3 started. The only thing we can say for sure is that the adventurer departing - presumably the main protagonist, seems to be armed with a gun and there's a body lying on the floor behind them.
The Fallout TV series stars Walton Goggins, Ella Purnell, Xelia Mendes-Jones and Kyle MacLachlan, is showrun by Geneva Robertson-Dworet and Graham Wagner, and is executive produced by Jonathan Nolan and Lisa Joy. The show has been filming since July in New Jersey, New York and Utah and is expected to wrap in the next few weeks. The show will likely debut on Amazon in the latter half of 2023.
Bethesda have celebrated the franchise's 25th anniversary by confirming an enhanced and updated version of Fallout 4 is coming to PC and next-generation consoles in 2023, and announcing that they will be moving onto development of Fallout 5 once work on their next two games, Starfield and The Elder Scrolls VI, is complete (so probably don't hold your breath on seeing it this decade).